You don't need to worry about partition alignment so much with iSCSI.
Apart from this NFS is in many respects superior. For example, there is no delete option in iSCSI (being SCSI over IP), so storage-layer thin provisioning is difficult to reclaim. In realtity the protocols are also very similar 'on the wire'.
However iSCSI has a perception advantage since that term has always been known to imply performance. Many looking at vmware won't have used NFS before.
http://blog.peacon.co.uk
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