it should work the same way assuming you're connecting to a remote SQL server and have the ODBC driver installed, the clients won't know that it's 64 bit runtime, only that it's SQL 2005
I agree it should work fine, but you probably will want to seperate the SQL server from the VC server.
Think of it like a file server running 64 bit OS, all the 32 bit clients can still connect. I know it's not apples to apples, but it should work fine.
Here's a couple other threads you may want to watch.
Looks like it works, and are just waiting for the official word.
url=http://www.vmware.com/community/thread.jspa?threadID=72661Topic: Installing SQL 2005 on 64bit and having VC2.0 connect to it.[/url]
url=http://www.vmware.com/community/thread.jspa?messageID=485896Topic: SQL 2005 and VC 2.x[/url]