Not sure which part are you concerning about having different uplinks/portgroups
However, If you have 4 Physical network adapters, you can split the North-South (External) and East-West to be on different uplinks.
See the 4 pNICs design below taken from the design guide VMware® NSX-T Reference Design
North-South are pinned to P1 & P2 while East-West are P3 & P4
This way you can offer symmetric bandwidth north-south/east-west because you dedicate themBayu Wibowo | VCIX6-DCV/NV
Author of VMware NSX Cookbook http://bit.ly/NSXCookbook
https://nz.linkedin.com/in/bayupw | twitter @bayupw