There are some VMs reside to the replication datastore will be vMotion from ClusterA to the ESXi hosts on ClusterB in the vCenter. There are other VMs on the replication datastore will remain on ClusterA. The replication is done on the storage side.
Does the SRM able to support protection group for the VMs in different cluster but reside on same replication datastore?
If yes, what are the configuration changes needed in the SRM?
If you inventory mappings such as resource,network,folder mappings are intact from cluster front. You should be good. It ideally does not matter if protection groups have VM's from different cluster provided that data store is shared across both the cluster.