we are running an ESX server (still 3.5 at the moment) which is connected to a cisco 6500 switch with two interfaces (no channel). the connections are trunks allowing two vlans as some virtual machines need to be in both subnets.
when a new machine is added the latency from the outside to virtual machines goes up, from say 7ms to 80-90ms. but when you ping the ESX server itself the response is still 7ms.
the way to solve this is to turn the trunk off on the cisco 6500 for the connected ports and then turn it on again, i.e.
set trunk x/y off
set trunk x/y on
after that the response times return to the normal 7ms.
does anyone know this situation and have an idea what might be the solution?