That's a great question.
I do not think it will cause a problem. I'm pretty sure it will be fine but I do not have an AMD box to test with to be sure.
If you want to test it I would do the following.
1. Clone the VSM
2. Disconnect all the NICs from the network on the cloned VSM VM (very important)
3. Migrate the clone VSM to the AMD box
4. See if it starts
Very important to make sure the cloned VSM has no network connectivity. If you leave the network attached you'll end up with two primary VSMs running on the same network with the same domain ID and that will cause all types of havoc.
I would say as long as the cloned VSM boots (which I'm 99% sure it will) I think you will be fine. Once you are happy it will work, delete the clone and plan your cold migration.
louis