Chris,
Used be that when you patched ESX you had to patch N1KV VEM modules as well. Since ESX 4.0U2 that is no longer the case. Our VEM modules are compatible with ESX patches that are in the same train.
If you are going from 4.0 to 4.1 a new VEM patch is required. If you are just patching 4.1 to 4.1U1 no new VEM module is required it will work with 4.1U1.
You can check out our compatibility matrix here
http://tinyurl.com/3trsa2m
louis