Express patch would be for a single bug critical bug fix or few critical bug fix depending on how much of code needs to be altered.
Updates would be cumulative of patches and EP released before it.
So, if you are on 5.5 and want to get to latest version, the suggestion would be to Go to the latest update release and if, there are any patches or EP released post the Update, then apply them post an ESXi U(x) update.
# Suhas
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Don't Backup. Go Forward!
Rubrik