I'm running ESXi 3.5U4 on an IBM 3650 with the latest updates that were released last week (sorry, didn't write down the version number).
Since this upgrade last week, I can not connect with the client, neither the vCenter client nor the vSphere client. If I reboot the server (from the console) I can connect with te client for a little while but once the server has run for a few hours, or a few days, I can no longer connect with any client. I get the following: