I have heard of some issue with fibre-channel target luns disappearing. Rebooting the server restores the connections. Using Qlogic 4Gb HBAs, 3.5 ESX.. Happens once in a while. More of a nuisance, no data is affected. Is this an initiator problem? Has anyone experienced similar issues? SAN system is not the culprit, happens with any FC target on a vaiety of boxes.
Very strange problem.
Do you have some strange configuration in ESX advanced options?
If you look at your datastore path you can see all green?
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