You will not find many best practise guides around as they are internal to Trend Micro and protected by none ddisclosure agreements.
Do you still need answers to the below as I can get them from my lab.
For the best practices there is a document from Trend Micro. you can find it here
There is also a recommended scan exclusion list, it is for Trend Micro Endpoint products in OfficeScan but also can be used as imput for Deep Security. you can find it here
I don't know if there are any free training's or videos.