Event Type: Error
Event Source: VMware VirtualCenter Server
Event Category: None
Event ID: 1000
Time: 9:33:30 AM
The description for Event ID ( 1000 ) in Source ( VMware VirtualCenter Server ) cannot be found. The local computer may not have the necessary registry information or message DLL files to display messages from a remote computer. You may be able to use the /AUXSOURCE= flag to retrieve this description; see Help and Support for details. The following information is part of the event: Failed to intialize VMware VirtualCenter. Shutting down....
You usually get that type of error when the VC server can't contact the VC database?
Is it on the same server?
If remote - is the DB server up?, can it be pinged?
Is the DB itself up, can you connect manually via the DSN?
Has anything changed?
Is this a new installation or after an upgrade?
If this is SQL 2005, the account you're running the Virtual Center service as must be the actual Databse Owner not just the db_Owner role. If it's 2000 it needs the db_Owner role.
If this is already true, verify the service pack levels required by your SQL version (including the Native Client for 2005).
have a look at the vpxd logs and also windows event viewer might give you a clue.
here is a nice document for troubleshooting