If you look at the supported OS's..... you'll see that it supports Windows 2003.....
"Supported Operating Systems: Windows Server 2003 Service Pack 2; Windows Server 2008; Windows Vista Service Pack 1; Windows XP Service Pack 3"
The client also supports a range of SQL database versions....
"Microsoft SQL Server 2008 Native Client (SQL Native Client) is a single dynamic-link library (DLL) containing both the SQL OLE DB provider and SQL ODBC driver. It contains run-time support for applications using native-code APIs (ODBC, OLE DB and ADO) to connect to Microsoft SQL Server 2000, 2005, or 2008"