@Chris_Nodak 

No we do not have that enabled. Looking through all of the tabs all I see is under Advanced we have enabled "Process during logon and logoff" (which might be the default). Also for reference we are running the following;

Windows 10 Enterprise 22H2
Horizon Agent 8.6.0.20088748
DEM Enterprise 10.6.0.1047
Google Chrome 111.0.5563.147
Google Drive 72.0.3.0

I also tried removing my Google DEM profile and starting from scratch with my login and it still persist through different sessions. I was curious/testing if it was working due to a previous profile with an earlier version of Chrome, however, that wasn't the case and for us it's working regardless of a new or existing Google DEM profiles.

Sorry if this isn't helping you out in your circumstance but trying to get you any possible data/info that may point out a difference between yours and ours.