Hello,
I do not know of anything that would cause performance issues. However, you may just want to run a few tests with common networking configurations with and without VXLAN. I do know however, that VXLAN will probably cross your physical switch boundaries at some point, so do they require a gateway or do they understand VXLAN, or just pass it through without getting in the way?
Best regards,
Edward L. Haletky
VMware Communities User Moderator, VMware vExpert 2009, 2010, 2011,2012,2013,2014
Author of the books 'VMWare ESX and ESXi in the Enterprise: Planning Deployment Virtualization Servers', Copyright 2011 Pearson Education. 'VMware vSphere and Virtual Infrastructure Security: Securing the Virtual Environment', Copyright 2009 Pearson Education.
Virtualization and Cloud Security Analyst: The Virtualization Practice, LLC -- vSphere Upgrade Saga -- Virtualization Security Round Table Podcast