I have attached the debug log below. This is using a standard profile (not mandatory) which is created afresh at each logon to prove the mandatory profile is not affecting the process
In this example, I deleted the logfile
Logged on at a Horizon desktop, changed some Word 2013 settings and some Wordpad settings
Logged off
Logged on at a different Horizon desktop
Opened Word - The setting were not retained
Opened Wordpad - The settings were retained
Thanks
Sean