Curious that you mention this, in the past we were working with RTX8000-2Q Profile and had allot of issues.
for testing purpose, we changed to 3Q Profiles and then the issues kind of came better ...
now all of the sudden it starts again, but then again software is getting heavier, and also the project are growing ...
Autodesk Civil 3D, Autodesk Revit ... Fire Simulation software (but that is CPU, not GPU)
my manager tries to avoid going to 4Q Profiles because the investment (VM per GPU) was calculated for 2Q profiles in the beginning.
tomorrow the issue will happen again for sure, so i make sure SSH is enabled and i check the Nvidia command to confirm whether it could be this that is causing the issue.
hypothetically speaking if this would be the case, should this be considered normal behaviour that a VM completely freezes because of this?? one would believe there should be safety mechanismes in place to ensure VM's don't go completely bananas 
Thanks for the feedback.