As above, you are not meant to run that on a fat machine it is made for base images and VM's.
I cant remember if that optimization tool has a reversal button and im not in front of my PC at the moment but to be honest, i would probably rebuilld your machine.
As for the slowness of it when your working at home -
Whats you connection at home like?
What protocol are you using - Blast/PCOIP?
Are you going through a VPN or direct?
