Hope you have created a Dedicated Pool.(Other wise User Data redirection will not happen)
On the VM , where agent is installed, check the PofileList path is correct or not. <The path should point to the Persistetn Disk>
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\ProfileList
Also what type of customization is used here (SysPrep / QuickPrep)
could pls attach logs ?
Regarding backup path:
The path is not allowded to changed through UI (But can change through preference file). alternatively you cna try the command line options for the backup. Refer View Admin guide , page 259
