for macs you must use vmware fusion!
12.1 works fine with osx big sur
But after this installation, it may be possible to install vsphere under fusion, but what will you do with this? With fusion you will have all possibilties to run virtual machines, windows 7,8,10, server, sles, rhed, and many others. And you can connect from fusion to any other vsphere server!
Try it, you will be enjoy!!!!
The product vmware Fusion is for mac, vmware Workstation for Windows
