I have a build where we are using a Firepro S7000 and I had been trying to get it working in passthrough. Under 4.1, had BSOD after going over 2GB RAM in the VM. Upgraded to ESXi 5.1, same thing. Tried pciHole.start fix under both versions with no positive impact. Upgraded again to 5.5 and now have passthrough working with 8GB RAM to a Citrix VM for publishing HW accelerated graphics apps. Performance is good so far, but I did have a problem like the poster above where the HDMI PCI device on the board would not pass through. Doesn't affect my build so we are just leaving it out.
Would like to be able to run VSGA with an AMD card in the near future. Is a VIB driver expected to be released, similar to the NVIDIA cards?