No round robin, our array has it's own pathing driver which looks correct. I think we've actually whittled it down to either A. a problem with the iSCSI initiator in VMware or B. our UCS config since the only hosts seeing any issues are UCS. All non-UCS hosts seem to have no issues.
Unfortunately we can't reboot these for awhile since the hosts having the issue are Cisco UC for the company which will require some scheduled down time. We have Cisco going over our UCS config to make sure there's nothing awry there first, and if not then we're going to reboot the hosts.