This happened once before in an earlier version of 16, and I attributed it to some fluke.

I'm running a test against our product, I have a snapshot right before a reproducible error case and was returning to a snapshot to run permutations on that test. But after 4 or 5 reverts to the pre-test snapshot, Workstation has lost the last disk update and the VM won't start anymore.

Event 1: Lost another snapshot file leaving the VM and snapshots useless.
Event 2: I've also had the .vmx file go missing, there might be a file handling bug in 16.
Event 3: This one.

I'm running:
Windows 10 Pro (21H1 / Build 19043.1586)
VMWare Workstation Pro: 16.2.3 build-19376536

No mentions of AV noticing VMWare or disk activity (BitDefender).
SSD is a barely used SATA Micron 5100