As above, you are not meant to run that on a fat machine it is made for base images and VM's.

I cant remember if that optimization tool has a reversal button and im not in front of my PC at the moment but to be honest, i would probably rebuilld your machine.

As for the slowness of it when your working at home -

Whats you connection at home like?

What protocol are you using - Blast/PCOIP?

Are you going through a VPN or direct?