Problem Solved:

I took my troubleshooting further and removed monitors one by one from the StarTech hub and tested. Using a single monitor going into the HDMI port I was able to use Unity. With a single monitor going into the DISPLAY port I was not able to use Unity. I also found that with the monitor using the DISPLAY port I was not able to change my display color profile.  Problem must be with the StarTech, Display cable, or StarTech display manager software.

In summary, when all else fails eliminate the physical layer. Start from 0 and work up from there. When I was troubleshooting I went to 0 using only the laptop and Unity worked. Then I went to a single HDMI monitor and found Unity worked and stopped there. Never testing the DISPLAY monitor.

Lesson learned. Hopefully this helps the next person as they are looking for a similar solution.