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Excluding the file yourself and sending to the AV company are two different things. If you send it to your AV company, they will actually fix the false positive in their next definition release (after they analyze to ensure it doesnt contain malware of course). At least that's how Symantec does it and I'm sure other AV companies have simular procedures. Do it all the time with homegrown software made by employees in our company and even commericial software that sometimes gets detected after some new def release. Doesn't lower security if you do it this way. Excluding things on your own is a different story (depending on if you exclude by specific file name, folder, file extension). I avoid those types of exclusions as much as possible.