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I would be interested in how one app took down the VMs and host. Do you have DRS and SIOC enabled? More details on how your hosts are configured with NICs, VLANs as well as storage such might be helpful. I have had guests that drive the host CPU to 100% and never impacted anything else as DRS and HBA tuning, etc all prevented that from happening. In the one cluster that we do mix DEV and PROD on we set the resources shares to DEV boxes at low, all other to normal and business critical VMs to HIGH for CPU and RAM. I am not a fan of resource pools as they create as many problems as they fix.

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