I see a few errors, on one of the first lines there is an APD state (all paths down to a storage device)
but, what i think is causing the issues is this:

2020-11-27T05:35:36.286Z cpu1:2097569)ScsiDeviceIO: 9777: Get VPD 86 Inquiry for device "naa.6b8ca3a0ef0ab60022ce1aee0ca031b6" from Plugin "NMP" failed. Not supported
2020-11-27T05:35:36.286Z cpu1:2097569)ScsiDeviceIO: 8461: Could not detect setting of QErr for device naa.6b8ca3a0ef0ab60022ce1aee0ca031b6. Error Not supported.


Your Multipath plugins are failing

Please check that all your hardware setup is on compatibility matrix and download latest drivers/firmware