to restart the network you can restart the init.d script (as you can with redhat) like '/etc/init.d/networking restart'.

but in the appliance you dont have to. in the bottom left there's a link to the appliance settings that lets you configure everything from the web interface. if you save that, the network is restarted automatically and the settings will work directly (no need to reboot).

i would use a dhcp number for the appliance if possible (all scripts and ks files it generates are changed automatically when the ip changes) but it runs it's own dhcp server so that wouldn't work too well.