Hi - Do you know which datastore is showing the latency? The graph attached was just for the whole host, it will help you narrow it down if you view it by datastore.
Usually ESXi is loaded into memory from the SD card so usually a faulty SD card wont take down the server straight away.
As you are not showing latenct when transferring at 150MB/s, it looks like it is a separate datastore that has the latency issue.