Hi
Yes, but only during the time of an upgrade. VMware does not support running different versions of these components under normal operations within a vSphere Domain.
Mixed-Version Support
Now, on to the questions mentioned earlier. The first question is, “Can I run vCenter Servers and Platform Services Controllers (PSCs) of different versions in my vSphere Domain?” The answer here is yes, but only during the time of an upgrade. VMware does not support running different versions of these components under normal operations within a vSphere Domain. The exact verbiage from the article is, “Mixed-version environments are not supported for production. Use these environments only during the period when an environment is in transition between vCenter Server versions.” So, do not plan on running different versions of vCenter Server and PSC in production on an ongoing basis.
Understanding the Impacts of Mixed-Version vCenter Server Deployments - VMware vSphere Blog
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Diego Oliveira
LinkedIn: http://www.linkedin.com/in/dcodiego