Lot depends upon End-End design in the overall datacenter. There is no thumb rule when it comes to multitenancy tenancy , NSX is flexible enough to fit with any designs . For a given
Scenario : Total of 5 tenants and each tenants have 5 VLANS and dedicated routing stack is required however there are few tenants which should be routable between themselves and rest of them doesn't need . In this case VDS design doesn't add much value , unless there is a requirements for VDS features for specific tenants and Uplink connectivity/speed differ across server models which will have a direct impact on tenant design.I hope you got my point. Like I said I would recommend keep VNI completely aside and consider VDS,TransportZone,DLR,Edges etc as the key criteria while designing. Just ensure there are no overlapping Segment-ID while doing cross VC designs.