Hi Cody!
Yes, it is possible, and yes, at least I have done some integration to CMDBs.
Unfortunately, the CMDB were always self-developments from the customer, so there is no "standard" way.
If the CMDB provides an API, try to use this (via webservice, or by calling local CLI-commands, or executing SSH, or. ...)
For the "bad", you can use the JDBC commands to access the database of the CMDB directly.
The best integration might be to write a Plugin for vCO....
Which CMDB do you have in mind?
Regards,
Joerg