ESX 3.5 on IBM xServer 445 disk storage EVA3000, when one of users copy files to a virtual server (Guest OS) (a standard copy to sharing folder from user's computer, nothing special) during a two-minute system stops responding, in Virtual Center I`m getting warning message:
Issue detected on esx01 in Datacenter: APIC: 1382: Lint1 interrupt on pcpu 0 (port x61 contains 0x35) (0:00:18.269 cpu0:1024)
and then the entire HOST server reboots! Whole ESX Server goes to reboot!
Updating server to U4 not resolves problem, the problem detected for all virtual machines (Guest OS) when copying files (3-4Gb) to Guest OS shared foleder diring file transfer kills entire ESX server.
If you can, you might try disabling all USB ports in your System BIOS and rebooting your ESX host to see if that makes any difference for you. What is the brand and model of NIC you're using in that server (Intel or Broadcom)?