We have an ESX 3.5 cluster that replicates over the WAN to another cluster in a DR site. Veeam is used to allow for duplications of VMs. In the middle is a local staging box where all the servers that replciate remotely go first, and also some very large local servers that only replicate locally. We have found that the replication falls over continually when it goes to the local staging server. This is a big problem, and we want to rebuild this server. I was just wondering what would happen if I rebuilt that server using Vsphere 4.1 instead of ESX 3.5? I know the former is a superior product (and we are licensed for it), but I was just wondering if it might cause problems mixing the versions of replciations partners. Thanks.
Basically I don't see an issue regarding the replication between different host versions (as long as Veeam supports 4.1). However adding a 4.1 host to vCenter 2.5 (which I assume you are running) is not possible and you would have to upgrade your vCenter Server first to be able to manager 4.1 hosts.
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Because Veeam is compatible with 3.x and 4.x the replication from 3.x to 4.x it's possible.
From 4.x to 3.x is not possible if VM use virtual hardware 7 instead of virtual hardware 4.