Multipathing is supported, see here:
Snapshots are fine as well. You can set options to remove old vcb snapshots, if they exist prior to vcb kicking off, and to remove the vcb helper snapshot when done. Other snapshots that you may have taken are left alone when VCB does its snapshot/backup/remove snapshot routine.
-KjB
vExpert/VCP/VCAP
vmwise.com / @vmwise
-KjB