Whenever I reboot my ESX host, I lose the iSCSI IP address in the software initiator settings. I've got to re-add the IP address and recan the bus. We just migrated everything from fiber storage to iSCSI. This is bad ...... REALLY bad.
We're running v3.02. I'll upgrade to 3.5 right now if somebody thinks that will fix it.
Strange that the IP goes away. Does the initiator itself stay enabled?
Did you allow it through the firewall? Configuration->security profile-> enable "Software iscsi client"
The first time that box came back unchecked. The next time I rebooted, the remained checked but the IP address went away.