Hi Heyeric,
You have to attach a Windows machine to MD3000 via SAS cables and install Microsoft iSCSI TARGET software on that Windows machine. Then from ESX servers, use buil-in iSCSI client to discover the iSCSI target from the Windows machine.
If you use MD3000i you don't need a Windows box and configure it as a iSCSI target as mentioned above. MD3000i has iSCSI targets built-in.
Typical solution for MD3000 is to hook it up with Dell's NX1950 servers (cluster) which comes with 64 bit Windows Unified Data Storage Server a long with some other nice features of VSS, Single Instance Storage (SIS) and folder level quotas and so on. But if you use this solution with ESX 3.5 it will be a complicated solution because you have so many dependencies from ESX to NX1950s to MD3000.
ESX 3.5 and MD3000i will be the prefered solution personally. If you already have bought it but not yet delivered or not yet implemented, I recommend to change it to MD3000i since the only difference is the storage controllers, everything else is the same.
Hope this answer your question.
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