Upgrading to the latest vCenter Patch to address the current vulnerability VMSA-2021-0020 from my current version 6.7.0.44000 to latest version 6.7.0.50000 will break anything on NSX-T Environment.
@Shahnawaz_Shaik Thanks for posting the question. It will not break anything in NSX-T. So far we have not observed any issues post patching.
@baijup Thanks for the information.