Has anyone experienced issues with Persona Managment/V2 folders not syncing? We have several users over the last few months who their profiles stop updating after experiencing no issues for months/years. One test we do is save a document to the desktop, reboot, when the user logs back in the document is gone.
Do you have any errors in the logs on the VDI or the Persona Management share? I would check there first, for sure. Most likely one of them is trying to sync, and the other is giving an error somewhere.