This should be possible no?
I do not see a reason it should be an issue. Here is a link to an article that talks about moving your vcenter database. I would deffinatly back it up before you start though.
Also the installation guide shows support for SQL Server 2008 check this document out.
http://www.vmware.com/pdf/vsphere4/r41/vsp_41_esx_vc_installation_guide.pdf
Thanks for the links! I'll check them out now.
Yes,
This is very much possible. I have done this once.