I'm having the same issue. Just upgraded from v5.4.4 to v5.5 and had no luck. I use 3 monitors (1/Main on top; 2 on the bottom left and 3 on the bottom right). I used to have my Virtual Desktop's main monitor on 2 (bottom left), extending the desktop to monitor 3, so I could work remotely on 2 monitors. All a sudden VMWare Horizon randomly started to choose monitor 3 as the primary monitor for my remote connection, which is very annoying (all new windows and icons will be on the right monitor now). It will default back to monitor 2 sometimes, but I need monitor 2 to be the primary (for the remote connection) always. The system admin of my remote desktop does not allow the "Primary Display" option to be changed, so I wonder what can be done on Horizon to fix this. Thanks.