with out downtime it's not possible, you required guest OS downtime . so the better way of migration is 1) create new data store using new storage LUN and power off guest VM and perform storage vmotion from old storage data store to new storage data store. 2) once it's done, power on and check the OS , old RDM LUN connectivity and services 3) after that make availability of new storage RDM LUNs to the clusters( which is the copy of old storage RDM ) 4) shutdown the guest and remove old RDM from guest and add new RDM in the same sequences 5) power on the guest and verify the data