Do you know if there is any update or patch for vsphere esxi 6.5 for this vulnerability?

[jcordova]

NodeJS System Information Library Command Injection (CVE-2021-21315) for vSphere ESXi 6.5

[maksym007]

Potentially there was a patch. But the question will be in downloading such. 

Officially you will not find it - I would suggest to open a ticket to VMware and asking them. 

Maybe they will provide you with a link 

[scott28tt]

Not according to this: https://www.vmware.com/security/advisories.html#search=CVE-2021-21315

Note that 6.5 is no longer a supported ESXi version, only 7.0 and later are.