Hello I get this on both of my ESXi Pis with my 64GB USB 3.1 Verbatim sticks.
Lost connectivity to the device mpx.vmhba32:C0:T0:L0 backing the boot filesystem /vmfs/devices/disks/mpx.vmhba32:C0:T0:L0. As a result, host configuration changes will not be saved to persistent storage.
Is this related to the known isse "USB flacky" ? Powersupply is 2.5A usbarbitrator is turned off.