Trouble reading from destination, error -2241 ( Destination index invalid/damaged)

I am running VDR v2 and have been runnign into this problem for a few days.  One of the back up hard drives has developed this problem and keeps failing a intrgirty check.  I have tried a few things to solve this but so far nothing has done it.  Unlike many of the articles I have seen, few deal with the 'Destination "/SCSI-0:1/" will be locked until integrity check succeeds.' issue.  I have tried rebooting the host, removing the lck files and few other solutions but nothing yet and there are no corrupted restore points either.

Has anyone else dealt with this and who can I fix this while saving the data on the drive?

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