Please have a look at a similar issue I posted last week. I see some similarities here...
I did not notice where the top bar is because it's autohiding, but I do have my primary monitor on the right and I'm experiencing strange scrolling issues, but only when using Horizon Client 5.4.0 (we also have Horizon 7.9).
(zhanglin999, did you see this post?)
Hey Mickeybyte2 - thank you for drawing my attention to your post as I did not see it. I had all my attention focused on the Win10 VDI, View Agent, VMware Tools, etc and did not think that it might be related to the newer View Client 5.4 that I had upgraded at the same time. I tried the just released newer 5.4.1 Client and that did not help my issue. Not really a surprise as there was nothing in the 5.4.1 release notes about mouse issues. I then rolled back to the View Client 5.3 and my issue has disappeared. Thanks for providing the bread crumb I needed to get the resolution I needed. There's no features I need in the 5.4 Client so will just stick with 5.3 for now.
Yeah, I see this. I just PM you about the build with possible fix and debug information. Please note me if you have any update. Thanks very much for your patient help. :-)
Our QE reproduced the mouse scroll issue when main display is set on the right monitor. And it will be addressed in the coming 5.4.2.
Thanks for reporting this issue.