We have seen this random issue several times over the past few years. It is for sure random and it has happened on several different builds of Chrome. We were never able to replicate it all the time and it went away on its own or went away with a newer build. So not much help, sorry. Is this on the latest version of Chrome Enterprise?
We are using the latest Version 74.0.3729.169 (Official Build) (64-bit).
The issue is totally random, as it seems affects only Windows 10 machines, we didn't notice it at Windows 7.
Have you tried disabling updates via gpo? We were having this issue and when we implemented some GPO settings, it seemed to go away.