We also originally started with PCoIP 3+ years ago and in the last year and a half migrated completely over to Blast. We had basically no issues converting over. The end users really only noticed that the resizing of the welcome screen upon connecting was faster on Blast, otherwise no one cared or noticed. We had maybe two users that complained about the blurry text in Office products (Needed the H.264 High Color Accuracy checked) and they were fine.
We use a mixture of old Lenovo desktop hardware thin clients (Stratodesk linux) and HP branded thin clients. No issues with Blast.
I do think that Blast is a little more heavy on CPU consumption when the desktops don't have vGPU's attached. (task workers, etc).
Thanks a lot for the feedback. Quick question: where is the H.264 High Color Accuracy setting? I'm not sure we're seeing the issue, but, I'm going to take a look. Is that in the ADMX?