Simple question. Is it OK to connect to NFS storage which is located on a different subnet from the VMkernel?
as long as the latency is low and then you can gigabit i see no reason why not ..
I don't know that there would be anything stopping you. Test.
I do this for backing up a few random ESX hosts using VDR - the storage is on NFS on a different VLAN but over gigabit. Hasn't hiccuped once yet after 4 or so months.